Sunday, 19 May 2013

Musings on Cholesterol




Some time ago I had a regular blood test done, to make sure everything is OK.  The blood needed for the test was drawn a little inexpertly – as you can see from the photos.  I only put the photos here because I don't have any of my cholesterol and it is nice to have photos in a blog  ...

When I got the results back my doctor said that everything was fine, except that I had hideously high levels of cholesterol.  They have always been on the high side, but this time they were very very high – 8.6, and only 2 of that is the supposedly good HDL, whereas the evil LDL makes up the rest.  Statins! exclaimed the doctor.  No way! said I.  We agreed on a moratorium of six months, where I would clean up my diet, exercise even harder, etc etc.

Instead of heading straight for the gymn I started to Google around, for weeks on end.  I am not going to write a long post about medical details, because other people have already done it and can do it better than me.  I have pasted several links below if you are interested.  I recommend the first one especially – it gives the results from the Norwegian Hunt 2 Study.

As a general rule, I like to do my own research, so first I researched cholesterol, and what caused high levels.  I already sort of knew that the body manufactures its own cholesterol, and if we reduce our dietary intake our body simply produces more, so eating less cholesterol rich food is pretty pointless.  So what else could I do?  Exercise helped, apparently, also all sorts of supplements and special foods. 

One evening I came across two interesting bits of information, in two different websites:  (a) Two thirds of all American adults over 50 have high cholesterol, (b) half of all people over 50 who have heart attacks have high cholesterol levels – ergo, fewer people with high cholesterol have heart attacks than those with low cholesterol!  Suddenly I became very suspicious indeed!  And then, on a whim, I googled, ‘Cholesterol is good for you!’

I found the Norwegian Hunt 2 Study, inter alia.  It was financed by the Norwegian government – not the pharmaceutical industry - went on for ten years, covered 65,000 people (half men, half women) and found that men with average to moderately high levels of cholesterol lived longest, whereas women lived the longer the higher their cholesterol levels were – even if that level was above 7!  Have a look at the study, all the information is there, graphs included.

After that I continued to search, and found any number of other studies:

·        Studies of old people in nursing homes in Austria and France and the US showed that the higher their cholesterol the longer the people lived;

·        Autopsy reports showed that people with high levels of cholesterol in their blood had no more plaques in their veins than people with low cholesterol;

·        Studies which showed that cholesterol protects the body from infections and diseases, which explains why people with high cholesterol levels live longer;

·        Studies which show how cholesterol repairs damaged tissues, which explains why cholesterol levels rise with increasing age – the older we get the more our bodies need to be repaired;

·        Studies which emphasise the need for good dental hygiene – the same bacteria that damage teeth and gums also attack the cardiovascular system – indeed, gum disease is a marker for future heart attacks;

·        Studies which show quite how many side effects statins have, including cancer – most statin trials only last a few months or years, and cancer takes many years to develop, too long to show up in the trials;

·        Studies which show that women experience a lot more side effects from statins than men, and gain no benefit from taking them;

·        Reports which show how studies which show statins to be beneficial are publicised widely, whereas studies which show the opposite get buried;

·        Studies which show that people who are on statins do not extend their life expectancy by a single day;

·        Studies/analyses which show that many of the benefits claimed by statins are actually attributable to cholesterol – people who are prescribed statins have had high cholesterol levels for much of their life, and continue to benefit from its protective effects for a number of years even after they start to take statins.

I could go on, but you get the message.  My conclusion is that I am grateful to my body for taking such good care of me by manufacturing so much of this wonderful substance cholesterol, and I am not going to interfere with its beneficial activities.

Several closing comments.  After all my research I am personally convinced that smoking, sugar, and refined carbohydrates damage the body and should be avoided as much as possible.  Exercise, sleep, good dental hygiene, a balanced diet, and a cheerful disposition are essential to a healthy and long life.  Not news to anyone, I dare say.  

Lastly, don’t believe what I tell you.  Go out there and do your research.  When you read of some study which says, X reduces Y by Z amount, ask the question, How does it effect life expectancy?  Because that’s what matters in the end.  If some drug or dietary regime lowers my chance of dieing from a heart attack but increases my risk of dieing from cancer or a respiratory disease just as much or more then what is the point?  Look at overall life expectancy, always.

An interesting case in point is what I read in the news yesterday, that breast cancer rates vary greatly from country to country.  When digging deeper it shows that countries with higher incidence of breast cancer also have a longer life expectancy - women live long enough to get breast cancer in these countries.  This is true of many cancers.

When considering statistics, always look at absolute figures.  An increase/decrease in risk of 50% sounds impressive, but if this is relative to a very small number it becomes irrelevant.  Like doubling your chances of winning the lottery.  Of course,  these relative numbers are the ones that tend to be reported .... 

And never confuse an association with causation!  Firemen don’t set fire to buildings, but they are present at almost every serious fire incident.  Doctors don’t kill patients, but they are present at almost every deathbed scene.  Just as Cholesterol is present at every heart attack - because it is busy repairing damaged tissues, not because it damaged them and caused the heart attack.

 I didn't manage to link these, just copy and paste and you will find them!

http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2753.2011.01767.x/pdf

http://qjmed.oxfordjournals.org/content/95/6/397.full

http://www.asbmb.org/asbmbtoday/asbmbtoday_article.aspx?id=18949

http://cindy-on-health.blogspot.co.uk/2011/12/cholesterol-and-statins-whos-hero-whos.html

http://drnevillewilson.com/2011/06/01/high-cholesterol-reduces-risks-in-elderly/



http://drmalcolmkendrick.org/